“Real-Time Assessment of Wellness and Disease in Daily Life,” by Dennis Ausiello and Scott Lipnick, published in the journal, Big Data (October 2015)

 

 

 

Dr. Dennis Ausiello, Ph.D., Chief of Medicine, Massachusetts General Hospital; Director, Center for Assessment Technology and Continuous Health (CATCH), Massachusetts General Hospital; Jackson Distinguished Professor of Clinical Medicine and Director, M.D./Ph.D. Program, Harvard Medical School; Member, National Academy of Medicine and American Academy of Arts and Sciences

Dr. Scott Lipnick, Ph.D., Scientific Director, Center for Assessment Technology and Continuous Health (CATCH), Massachusetts General Hospital; Assistant in Biomedical Physics, Dept. of Medicine, Massachusetts General Hospital; Imaging and Data Specialist, Stem Cell and Regenerative Biology Dept., Harvard University

ABSTRACT

The next frontier in medicine involves better quantifying human traits, known as “phenotypes.” Biological markers have been directly associated with disease risks, but poor measurement of behaviors such as diet and exercise limits our understanding of preventive measures. By joining together an uncommonly wide range of disciplines and expertise, the Kavli HUMAN Project will advance measurement of behavioral phenotypes, as well as environmental factors that impact behavior. By following the same individuals over time, KHP will liberate new understanding of dynamic links between behavioral phenotypes, disease, and the broader environment. As KHP advances understanding of the bio-behavioral complex, it will seed new approaches to the diagnosis, prevention, and treatment of human disease.